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Overcome Male Infertility – What is Biochemical Analysis?

As discussed in previous articles, infertility is defined as the inability of a couple to conceive after 12 months of unprotected intercourse. It affects more than 5 million couples in the US alone and many times more worldwide. Due to the lack of knowledge of the treatments, only 10% seek help from a professional specialist. In this article, we will talk about what is the biochemical analysis of male infertility?

I. Definition

Study of the chemicals and vital processes that occur in the male testicle, such as the concentration of white blood cells, the level of fructose in the semen, and the volume, pH, and liquefaction time of the ejaculate.

II. Procedure

The sperm semen sample is taken in the clinic laboratory by masturbation, the semen is sent for analysis of chemical substances and vital processes as mentioned in the definition.

III. diagnosis

This test a semen analysis usually for

1. Volume

The semen sample required for this test is not less than 2.0 ml or more

It measures the number of sperm per milliliter (ml) of ejaculate

2. pH

pH is a measure of the acidity or basicity of a solution (a pH of 07 is considered neutral). In this test, 7.2 to 8.0 is required to be considered normal.

3. Sperm concentration

It measures the number of sperm per milliliter of ejaculate, for a normal sperm concentration 20,000,000 per ml or more is required.

4. Motility

Motility is a measure of sperm for movement, normal sperm motility is 50% or more with forward progression. It can be classified in 4th grade

a) Sperm with progressive motility:

These are the strongest and swim fast in a straight line

b) Non-linear motility: These also move forward but tend to travel in a curved or crooked motion.

c) Non-progressive motility:

Sperm do not move forward despite wagging their tails.

d) Non-motility:

Can’t move at all.

5. Rapid forward progressive motility

The sperm sample needs to have at least 25% or more of this type of sperm to be considered normal.

6. Morphology

It is the study of the normal and abnormal shape of spermatozoa. It was considered normal if it is

a) 30% or more of normal forms (WHO criteria)

b) 11% or more normal forms (strict Tygerberg criteria developed by Dr. Roelof Menkveld, Tygerberg Hospital, South Africa, and disseminated by Dr. Thinus Kruger)

7. Vitality

The sample must have at least 75% live sperm in a semen sample

8. White blood cells

The sample must have a white blood cell count of less than 1,000,000 per ml. Otherwise, it may be an indication of immune infertility causes and more testicles are required.

Sometimes the semen sample can also be tested for vesicular function, citrate or acid phosphatase for the prostate gland, and free carnitine as an index of epididymal function, if requested by your fertility specialist.

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